A Southwest Oncology Group study on the use of a human tumor cloning assay for predicting response in patients with ovarian cancer.

@article{Hoff1991ASO,
  title={A Southwest Oncology Group study on the use of a human tumor cloning assay for predicting response in patients with ovarian cancer.},
  author={Daniel Von Hoff and Richard A. Kronmal and Sydney Salmon and Janette Turner and Jeremy B. A. Green and J S Bonorris and Everard Moorhead and Harry E. Hynes and R. E. Pugh and Robert J. Belt},
  journal={Cancer},
  year={1991},
  volume={67 1},
  pages={20-7}
}
A total of 211 patients with epithelial ovarian cancer (168 with tumors refractory to prior chemotherapy and 43 with no prior chemotherapy) from 33 different Southwest Oncology Group institutions had their tumors sampled and specimens shipped to two central laboratories for drug-sensitivity testing in a human tumor cloning assay. The 168 patients with a prior history of chemotherapy failure (median of four prior chemotherapeutic agents) were treated with the most effective agent(s) found in the… CONTINUE READING

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