A Somitic Compartment of Tendon Progenitors

@article{Brent2003ASC,
  title={A Somitic Compartment of Tendon Progenitors},
  author={Ava E. Brent and Ronen Schweitzer and Clifford J. Tabin},
  journal={Cell},
  year={2003},
  volume={113},
  pages={235-248}
}
We demonstrate that the tendons associated with the axial skeleton derive from a heretofore unappreciated, fourth compartment of the somites. Scleraxis (Scx), a bHLH transcription factor, marks this somitic tendon progenitor population at its inception, and is continuously expressed through differentiation into the mature tendons. Two earlier-formed somitic compartments, the sclerotome and myotome, interact to establish this fourth Scx-positive compartment. The tendon progenitors are induced at… Expand
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