A Small Intestinal Organoid Model of Non-invasive Enteric Pathogen-Epithelial Cell Interactions

@inproceedings{Wilson2015ASI,
  title={A Small Intestinal Organoid Model of Non-invasive Enteric
Pathogen-Epithelial Cell Interactions},
  author={Sarah S. Wilson and Autumn Tocchi and Mayumi K Holly and William C. Parks and Jason G Smith},
  booktitle={Mucosal Immunology},
  year={2015}
}
Organoids mirror in vivo tissue organization and are powerful tools to investigate the development and cell biology of the small intestine. However, their application for the study of host–pathogen interactions has been largely unexplored. We have established a model using microinjection of organoids to mimic enteric infection, allowing for direct… CONTINUE READING