A Simple and Rapid Gene Disruption Strategy in Mycobacterium abscessus: On the Design and Application of Glycopeptidolipid Mutants

@inproceedings{Viljoen2018ASA,
  title={A Simple and Rapid Gene Disruption Strategy in Mycobacterium abscessus: On the Design and Application of Glycopeptidolipid Mutants},
  author={Albertus J. Viljoen and Ana Victoria Guti{\'e}rrez and Christian Dupont and {\'E}ric Ghigo and Laurent Kremer},
  booktitle={Front. Cell. Infect. Microbiol.},
  year={2018}
}
Little is known about the disease-causing genetic determinants that are used by Mycobacterium abscessus, increasingly acknowledged as an important emerging pathogen, notably in cystic fibrosis. The presence or absence of surface exposed glycopeptidolipids (GPL) conditions the smooth (S) or rough (R) M. abscessus subsp. abscessus (M. abscessus) variants… CONTINUE READING