A Simple Screen to Identify Promoters Conferring High Levels of Phenotypic Noise

@article{Freed2008ASS,
  title={A Simple Screen to Identify Promoters Conferring High Levels of Phenotypic Noise},
  author={Nikki E. Freed and Olin K. Silander and B{\"a}rbel Stecher and Alex R. Boehm and Wolf-Dietrich Hardt and Martin Ackermann},
  journal={PLoS Genetics},
  year={2008},
  volume={4},
  pages={69 - 73}
}
Genetically identical populations of unicellular organisms often show marked variation in some phenotypic traits. To investigate the molecular causes and possible biological functions of this phenotypic noise, it would be useful to have a method to identify genes whose expression varies stochastically on a certain time scale. Here, we developed such a method and used it for identifying genes with high levels of phenotypic noise in Salmonella enterica ssp. I serovar Typhimurium (S. Typhimurium… CONTINUE READING
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