A Short Receptor Downregulates JAK/STAT Signalling to Control the Drosophila Cellular Immune Response

Abstract

The posterior signalling centre (PSC), a small group of specialised cells, controls hemocyte (blood cell) homeostasis in the Drosophila larval hematopoietic organ, the lymph gland. This role of the PSC is very reminiscent of the "niche," the micro-environment of hematopoietic stem cells in vertebrates. We have recently shown that the PSC acts in a non-cell… (More)
DOI: 10.1371/journal.pbio.1000441

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@inproceedings{Makki2010ASR, title={A Short Receptor Downregulates JAK/STAT Signalling to Control the Drosophila Cellular Immune Response}, author={Rami Makki and Marie Meister and Delphine Pennetier and J Ubeda and Anne Sofie Braun and Virginie Daburon and Joanna Krzemień and Henri-Marc Bourbon and Rui Zhou and Alain Vincent and Mich{\'e}le Crozatier}, booktitle={PLoS biology}, year={2010} }