A Self-Organized Model for Cell-Differentiation Based on Variations of Molecular Decay Rates

@article{Hanel2012ASM,
  title={A Self-Organized Model for Cell-Differentiation Based on Variations of Molecular Decay Rates},
  author={Rudolf Hanel and Manfred P{\"o}chacker and Manuel Sch{\"o}lling and Stefan Thurner},
  journal={PLoS ONE},
  year={2012},
  volume={7}
}
Systemic properties of living cells are the result of molecular dynamics governed by so-called genetic regulatory networks (GRN). These networks capture all possible features of cells and are responsible for the immense levels of adaptation characteristic to living systems. At any point in time only small subsets of these networks are active. Any active subset of the GRN leads to the expression of particular sets of molecules (expression modes). The subsets of active networks change over time… 

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