A Selective Culture System for Generating Terminal Deoxynucleotidyl Transferase-Positive Lymphoid Cells In Vitro. V. Detection of Stage-Specific Pro-B-Cell Stimulating Activity in Medium Conditioned by Mouse Bone Marrow Stromal Cells

Abstract

The selective in vitro generation of rat, mouse, and human terminal deoxynucleotidyl transferase-positive (TdT+) lymphoid cells in our long-term xenogeneic bone marrow (BM) culture system is characterized by physical interaction between the developing lymphocytes and mouse BM-adherent stromal cells and macrophages. In the present study, experiments in which… (More)

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@article{Mckenna1993ASC, title={A Selective Culture System for Generating Terminal Deoxynucleotidyl Transferase-Positive Lymphoid Cells In Vitro. V. Detection of Stage-Specific Pro-B-Cell Stimulating Activity in Medium Conditioned by Mouse Bone Marrow Stromal Cells}, author={Sean D. Mckenna and Irving Goldschneider}, journal={Developmental Immunology}, year={1993}, volume={3}, pages={181 - 195} }