A Schistosoma mansoni epitope recognized by a protective monoclonal antibody is identical to the stage-specific embryonic antigen 1.

@article{Ko1990ASM,
  title={A Schistosoma mansoni epitope recognized by a protective monoclonal antibody is identical to the stage-specific embryonic antigen 1.},
  author={Albert Icksang Ko and Ursula C. Dr{\"a}ger and Donald A. Harn},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1990},
  volume={87 11},
  pages={4159-63}
}
In infections with the parasitic trematode Schistosoma mansoni, a component of the host defense is directed against the invading larval form, and carbohydrates on the surface of these larvae are targets for the immune attack during the early stages of infection. To identify such carbohydrate epitopes, which may be suitable for immunization against schistosomiasis, we have previously generated monoclonal antibodies to surface antigens; some of these confer protection to naive mice when passively… CONTINUE READING
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