A SPIKE1 signaling complex controls actin-dependent cell morphogenesis through the heteromeric WAVE and ARP2/3 complexes.

@article{Basu2008ASS,
  title={A SPIKE1 signaling complex controls actin-dependent cell morphogenesis through the heteromeric WAVE and ARP2/3 complexes.},
  author={Dipanwita Basu and Jie Le and Taya Zakharova and Eileen L. Mallery and Daniel B Szymanski},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2008},
  volume={105 10},
  pages={4044-9}
}
During morphogenesis, the actin cytoskeleton mediates cell-shape change in response to growth signals. In plants, actin filaments organize the cytoplasm in regions of polarized growth, and the filamentous arrays can be highly dynamic. Small GTPase signaling proteins termed Rho of plants (ROP)/RAC control actin polymerization. ROPs cycle between inactive GDP-bound and active GTP-bound forms, and it is the active form that interacts with effector proteins to mediate cytoskeletal rearrangement and… CONTINUE READING
44 Extracted Citations
35 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 44 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 35 references

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

  • Cote J-F, K Vuori
  • J Cell Sci 115:4901–4913
  • 2002
Highly Influential
5 Excerpts

The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis

  • JF Uhrig
  • Development
  • 2007
1 Excerpt

growth requires two antagonistic pathways with opposing action on cell morphogenesis

  • M Lavy
  • 2007

Similar Papers

Loading similar papers…