A SARS-CoV protein, ORF-6, induces caspase-3 mediated, ER stress and JNK-dependent apoptosis.

@article{Ye2008ASP,
  title={A SARS-CoV protein, ORF-6, induces caspase-3 mediated, ER stress and JNK-dependent apoptosis.},
  author={Zhongde Ye and Chung Kai Wong and Peng Li and Yong Xie},
  journal={Biochimica et biophysica acta},
  year={2008},
  volume={1780 12},
  pages={1383-7}
}
Severe acute respiratory syndrome (SARS) coronavirus (CoV) spread from China to more than 30 countries, causing severe outbreaks of atypical pneumonia and over 800 deaths worldwide. CoV primarily infects the upper respiratory and gastrointestinal tract; however, SARS-CoV has a unique pathogenesis because it infects both the upper and lower respiratory… CONTINUE READING