Corpus ID: 58661200

A Role for Orexin Neuron Activity in Cytotoxic Chemotherapy-Induced Fatigue

@inproceedings{Weymann2013ARF,
  title={A Role for Orexin Neuron Activity in Cytotoxic Chemotherapy-Induced Fatigue},
  author={K. Weymann},
  year={2013}
}
Background Fatigue is the most common symptom related to cytotoxic chemotherapeutic treatment of cancer. Peripheral inflammation associated with cytotoxic chemotherapy is likely a causal factor of fatigue. However, the neural mechanisms by which cytotoxic chemotherapy associated inflammation induces fatigue behavior are not known. This lack of knowledge hinders development of interventions to reduce or prevent this disabling symptom. Infection induced fatigue/lethargy in rodents is mediated by… Expand
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