A Role for Nitric Oxide-Driven Retrograde Signaling in the Consolidation of a Fear Memory

@inproceedings{Overeem2010ARF,
  title={A Role for Nitric Oxide-Driven Retrograde Signaling in the Consolidation of a Fear Memory},
  author={Kathie A. Overeem and Kristie T. Ota and Melissa S. Monsey and Jonathan E Ploski and Glenn E. Schafe},
  booktitle={Front. Behav. Neurosci.},
  year={2010}
}
In both invertebrate and vertebrate models of synaptic plasticity, signaling via the putative "retrograde messenger" nitric oxide (NO) has been hypothesized to serve as a critical link between functional and structural alterations at pre- and postsynaptic sites. However, while in vitro models of synaptic plasticity have consistently implicated NO signaling in linking postsynaptic induction mechanisms with accompanying presynaptic changes, a convincing role of such "retrograde signaling" in… CONTINUE READING