A Role for Innexin2 and Innexin3 Proteins from Spodoptera litura in Apoptosis

@article{Liu2013ARF,
  title={A Role for Innexin2 and Innexin3 Proteins from Spodoptera litura in Apoptosis},
  author={Tian Cheng Liu and Ming Li and Yan Zhang and Zunyu Pang and Wei Xiao and Yang Yang and Kaijun Luo},
  journal={PLoS ONE},
  year={2013},
  volume={8}
}
Gap junctions formed by two hemichannels from two neighboring cells are cell-to-cell communication channels; hemichannels are communication channels between intracellular and extracellular environments. Hemichannels are hexameric proteins formed by connexins, pannexins, innexins and vinnexins. Innexin-hemichannels (innexons) exist in the lepidopteran cell surface, but their component innexins and functions have not been reported. Recent studies by others have demonstrated that hemichannels… 

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TWO INNEXINS OF Spodoptera litura INFLUENCES HEMICHANNEL AND GAP JUNCTION FUNCTIONS IN CELLULAR IMMUNE RESPONSES.
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A steady-state level of Inxs (SpliInxs) was reported in hemocytes of Spodoptera litura, which formed nonfunctional hemichannels on the cell surface to maintain normal metabolism and provides fundamental knowledge for further study of how steady- state levels of SpliInx are dynamically adjusted to perform cellular immune responses under immune challenge.
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Bracovirus Sneaks Into Apoptotic Bodies Transmitting Immunosuppressive Signaling Driven by Integration-Mediated eIF5A Hypusination
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