A Rho-dependent phase-variable transcription terminator controls expression of the FimE recombinase in Escherichia coli.

@article{Joyce2002ARP,
  title={A Rho-dependent phase-variable transcription terminator controls expression of the FimE recombinase in Escherichia coli.},
  author={Susan A. Joyce and Charles J Dorman},
  journal={Molecular microbiology},
  year={2002},
  volume={45 4},
  pages={1107-17}
}
The fim switch is a 314 bp segment of invertible chromosomal DNA that is responsible for phase-variable expression of type 1 fimbriae in Escherichia coli. The switch harbours the promoter of the fimA gene. This codes for the type 1 fimbrial subunit protein and, when the promoter is directed towards fimA (phase ON), the bacteria are fimbriate and, when it is directed away, the cells are afimbriate. The switch lies immediately downstream from the fimE gene, coding for a tyrosine site-specific… CONTINUE READING

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