A Rh(ii)-catalyzed three-component reaction of 3-diazooxindoles with N,N-disubstituted anilines and glyoxylates for the synthesis of 3-aryl-3-substituted oxindoles.

Abstract

A simple and effective method for the synthesis of 3-aryl-3-substituted oxindole derivatives via a [Rh]-catalyzed three-component reaction of 3-diazooxindoles with N,N-disubstituted anilines and glyoxylates is developed. This transformation is proposed to proceed through an intermolecular aldol-type trapping of zwitterionic intermediates.

Cite this paper

@article{Jia2016ART, title={A Rh(ii)-catalyzed three-component reaction of 3-diazooxindoles with N,N-disubstituted anilines and glyoxylates for the synthesis of 3-aryl-3-substituted oxindoles.}, author={Shi-Kun Jia and Long-long Song and Yu-Bing Lei and A Gopi Krishna Reddy and Dong Xing and Wenhao Hu}, journal={Organic & biomolecular chemistry}, year={2016}, volume={14 43}, pages={10157-10160} }