A Revised Hemodynamic Theory of Age-Related Macular Degeneration.

  title={A Revised Hemodynamic Theory of Age-Related Macular Degeneration.},
  author={Bradley D. Gelfand and Jayakrishna Ambati},
  journal={Trends in molecular medicine},
  volume={22 8},
Age-related macular degeneration (AMD) afflicts one out of every 40 individuals worldwide, causing irreversible central blindness in millions. The transformation of various tissue layers within the macula in the retina has led to competing conceptual models of the molecular pathways, cell types, and tissues responsible for the onset and progression of AMD. A model that has persisted for over 6 decades is the hemodynamic, or vascular theory of AMD progression, which states that vascular… CONTINUE READING
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