A Review of the Role of Anticholinergic Activity in Lewy Body Disease and Delirium.

Abstract

We have previously proposed a hypothesis in which we argue that anticholinergic activity (AA) appears endogenously in Alzheimer's disease (AD). Acetylcholine (ACh) controls both cognitive function and inflammation. Consequently, when the downregulation of ACh reaches critical levels, the inflammatory system is upregulated and proinflammatory cytokines with… (More)
DOI: 10.1159/000381522

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