A Review of the Molecular Genetics of Congenital Idiopathic Nystagmus (CIN)

@article{Self2007ARO,
  title={A Review of the Molecular Genetics of Congenital Idiopathic Nystagmus (CIN)},
  author={James Self and Andrew John Lotery},
  journal={Ophthalmic Genetics},
  year={2007},
  volume={28},
  pages={187 - 191}
}
Congenital Idiopathic Nystagmus (CIN) is genetically heterogeneous. Autosomal dominant, autosomal recessive and X-linked patterns of inheritance have been reported. Linkage analysis has suggested the existence of at least three distinct loci for both autosomal dominant and X-linked forms, although only one disease gene has been identified (FRMD7, Xq26.2). The pathophysiological mechanisms underlying nystagmus are poorly understood but it is anticipated that characterization of the FRMD7 gene… 
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