A Review of the Medicinal Plants of Genus Orthosiphon (Lamiaceae)

@article{Singh2015ARO,
  title={A Review of the Medicinal Plants of Genus Orthosiphon (Lamiaceae)},
  author={Mukesh Kr. Singh and Bina Gidwani and Anshita Gupta and Hemant J. Dhongade and Pranita Kashyap and Dulal Krishna Tripathi},
  journal={International Journal of Biological Chemistry},
  year={2015},
  volume={9},
  pages={318-331}
}
In the genus Orthosiphon (Lamiaceae), Orthosiphon aristatus, Orthosiphon pallidus, Orthosiphon thymiflorus, Orthosiphon stamineus are widely used in traditional medicine to prevent different diseases such as diabetes, kidney stone, edema, rheumatism, hepatitis, hypertensive and jaundice. A different variety of phytoconstituents has been isolated from the Orthosiphon species which include monoterpenes, diterpenes, triterpenes, saponins, organic acid and flavonoids compound. Antidiabetic, anti… Expand

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References

SHOWING 1-10 OF 62 REFERENCES
A SURVEY OF THE CHEMICAL CONSTITUENTS AND BIOLOGICAL ACTIVITIES OF ORTHOSIPHON STAMINEUS
TLDR
The plant has also been reported to possess various novel secondary metabolites such as diterpenes, flavones and triterpene. Expand
Orthosiphon stamineus: traditional uses, phytochemistry, pharmacology, and toxicology.
TLDR
A comprehensive summary of the currently available chemical, pharmacological, and toxicological investigations as well as the traditional and therapeutic uses of O. stamineus finds that it has wide traditional and pharmacological uses in various pathophysiological conditions. Expand
Isolation and characterization of triterpenes from the leaves of Orthosiphon stamineus
Abstract Orthosiphon stamineus , Benth, belonging to the family Lamiaceae, is a medicinal plant growing wild in tropical countries. Seven triterpenes, ursolic acid, oleanolic acid, betulinic acid,Expand
FROM ETHNOPHARMACOLOGY TO CLINICAL STUDY OF ORTHOSIPHON STAMINEUS BENTH.
TLDR
This report comprehensively reviews ethnopharmacological, isolated chemical compounds, pharmacological, toxicological and clinical studies of O. stamineus and meets its scientific evidence in aspects of phytochemical, Pharmacological, Toxicological as well as clinical. Expand
Phytochemical and pharmacological studies on Orthosiphon stamineus Benth. (Lamiaceae) hydroalcoholic extracts.
The main components of Orthosiphon stamineus Benth. leaves and extracts are the pharmacologically active polyphenols: the polymethoxylated flavonoids and the caffeic acid derivatives. Two tinctures,Expand
Antioxidant and anti-inflammatory effects of Orthosiphon aristatus and its bioactive compounds.
TLDR
EEOA and its bioactive compound, ursolic acid, suppress LPS-induced NO and PGE(2) production by inhibiting ROS generation, along with reducing expression of iNOS and COX-2 in RAW 264.7 cells. Expand
Indonesian Medicinal Plants. XXII. Chemical Structures of Two New Isopimarane-Type Diterpenes, Orthosiphonones A and B, and a New Benzochromene, Orthochromene A from the Leaves of Orthosiphon aristatus (Lamiaceae)
Two new isopimarane-type diterpenes named orthosiphonones A and B and a new benzochromene named orthochromene A, have been isolated from the water decoction of the leaves of Orthosiphon aristatusExpand
Indonesian medicinal plants. XXIII. Chemical structures of two new migrated pimarane-type diterpenes, neoorthosiphols A and B, and suppressive effects on rat thoracic aorta of chemical constituents isolated from the leaves of Orthosiphon aristatus (Lamiaceae).
Two novel migrated pimarane-type diterpenes named neoorthosiphols A (1) and B (2) were isolated from the water decoction of the leaves of Orthosiphon aristatus (Lamiaceae), which has been prescribedExpand
Diterpenoids from the aerial parts of Orthosiphon aristatus var. aristatus
TLDR
Seven new isopimarane diterpenoids, orthoarisins A−G, together with 15 previously reported diter penoids were isolated from the aerial parts of Orthosiphon aristatus var. Expand
Effect of extracts of Orthosiphon stamineus benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva‐ursi (L.) spreng. in rats
Aqueous extracts of Sambucus nigra and Arctostaphylos uva‐ursi and hydroalcohol extracts of Orthosiphon stamineus and Hieracium pilosella were tested for their diuretic activities in rats;Expand
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