A Review of Trimipramine 30 Years of Clinical Use

  title={A Review of Trimipramine 30 Years of Clinical Use},
  author={Yvon D. Lapierre},
SummaryThe hybrid chemical structure of trimipramine incorporates an imipramine nucleus and levomepromazine side chain. This structure predicts much of the clinical profile of trimipramine.The initial studies on trimipramine date back nearly 30 years. It now has a well-recognised clinical profile with some characteristics akin to other tricyclic antidepressants (TCA) and others which are quite distinct. It is well established as a highly effective antidepressant with an efficacy profile similar… 

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