A Review of Ribonuclease 7’s Structure, Regulation, and Contributions to Host Defense

@inproceedings{Becknell2016ARO,
  title={A Review of Ribonuclease 7’s Structure, Regulation, and Contributions to Host Defense},
  author={Brian Becknell and John David Spencer},
  booktitle={International journal of molecular sciences},
  year={2016}
}
The Ribonuclease A Superfamily is composed of a group of structurally similar peptides that are secreted by immune cells and epithelial tissues. Several members of the Ribonuclease A Superfamily demonstrate antimicrobial activity, and it has been suggested that some of these ribonucleases play an essential role in host defense. Ribonuclease 7 (RNase 7) is an epithelial-derived secreted peptide with potent broad-spectrum antimicrobial activity. This review summarizes the published literature on… CONTINUE READING
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