• DOI:10.3821/1913-701X-142.5.248
Corpus ID: 56795699

A Retrospective Review Assessing the Efficacy and Safety of Nitrofurantoin in Renal Impairment

@article{Bains2009ARR,
  title={A Retrospective Review Assessing the Efficacy and Safety of Nitrofurantoin in Renal Impairment},
  author={Ajay Bains and Donna Buna and N. Hoag},
  journal={Canadian Pharmacists Journal / Revue des Pharmaciens du Canada},
  year={2009},
  volume={142},
  pages={248 - 252}
}

Ajay Bains, Donna Buna, N. Hoag

Published 2009

Medicine

Canadian Pharmacists Journal / Revue des Pharmaciens du Canada

Background: Nitrofurantoin (NF) is an antibiotic commonly used to treat uncomplicated urinary tract infections (UTIs). Although NF is contraindicated in patients with an estimated glomerular filtration rate (GFR) of less than 60 mL/min, the evidence demonstrating its lack of efficacy and an increased rate of adverse reactions in these patients is marginal. Methods: A retrospective chart review was conducted to determine the efficacy and safety of NF in patients with a UTI and an estimated GFR… CONTINUE READING

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