A Reliable Biomarker Derived from Plasmalogens to Evaluate Malignancy and Metastatic Capacity of Human Cancers

@article{Smith2007ARB,
  title={A Reliable Biomarker Derived from Plasmalogens to Evaluate Malignancy and Metastatic Capacity of Human Cancers},
  author={Rosina E. Smith and Pablo Javier Lespi and Maria Luca and C. Larraya Bustos and Fernando Ariel Marra and Monica Alaniz and Carlos Alberto Marra},
  journal={Lipids},
  year={2007},
  volume={43},
  pages={79-89}
}
Antigen tumor markers employed in monitoring therapeutical approaches are limited by their specificity (Sp) and sensitivity (Se). The aim of this study was to investigate the suitability of a lipid tumor marker derived from ether-linked phospholipids and to compare it with others usually assayed in clinical practice. Complex lipids from normal and pathological breast, lung, and prostate tissue were isolated and analyzed by TLC and c-GLC methods. Results were compared as pooled samples, or by… CONTINUE READING
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