A Reference Methylome Database and Analysis Pipeline to Facilitate Integrative and Comparative Epigenomics

Abstract

DNA methylation is implicated in a surprising diversity of regulatory, evolutionary processes and diseases in eukaryotes. The introduction of whole-genome bisulfite sequencing has enabled the study of DNA methylation at a single-base resolution, revealing many new aspects of DNA methylation and highlighting the usefulness of methylome data in understanding… (More)
DOI: 10.1371/journal.pone.0081148

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