A Recombinant Tail-Less Integrin/34 Subunit Disrupts Hemidesmosomes, but Does Not Suppress otd34-mediated Cell Adhesion to Laminins

Abstract

To examine the function of the c~d~4 integrin we have determined its ligand-binding ability and overexpressed two potentially dominant negative mutant ~4 subunits, lacking either the cytoplasmic or extracellular domain, in bladder epithelial 804G cells. The results of cell adhesion and radioligand-binding assays showed that O/6~4 is a receptor for several… (More)

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@inproceedings{Spinardi1995ART, title={A Recombinant Tail-Less Integrin/34 Subunit Disrupts Hemidesmosomes, but Does Not Suppress otd34-mediated Cell Adhesion to Laminins}, author={Laura Spinardi}, year={1995} }