A Randomized Prospective Trial to Assess the Role of Saline Hydration on the Development of Contrast Nephrotoxicity

@article{Trivedi2003ARP,
  title={A Randomized Prospective Trial to Assess the Role of Saline Hydration on the Development of Contrast Nephrotoxicity},
  author={Hariprasad S. Trivedi and Harold F. Moore and Samer Nasr and Kul B Aggarwal and Alok Agrawal and Punit Goel and John R. Hewett},
  journal={Nephron Clinical Practice},
  year={2003},
  volume={93},
  pages={c29 - c34}
}
Though simple and attractive, the role of hydration for the prophylaxis of contrast nephrotoxicity has not been definitively established. We prospectively evaluated the role of deliberate saline hydration in patients undergoing nonemergency cardiac catheterization. Patients (n = 53) were randomized on the day prior to scheduled catheterization to one of two groups – group 1 (n = 27) received normal saline for 24 h (at a rate of 1 ml/kg/h) beginning 12 h prior to scheduled catheterization, and… CONTINUE READING

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