A Randomized Placebo-Controlled Trial of Acetaminophen for Prevention of Post-Vaccination Fever in Infants

@inproceedings{Jackson2011ARP,
  title={A Randomized Placebo-Controlled Trial of Acetaminophen for Prevention of Post-Vaccination Fever in Infants},
  author={Lisa A. Jackson and Do Peterson and John B Dunn and Simon J. Hambidge and Maya Dunstan and Patty Starkovich and Onchee Yu and Joyce Benoit and Clara Pen{\'e}lope Dom{\'i}nguez-Islas and Barbara A Carste and Patti Benson and Jennifer C. Nelson},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND Fever is common following infant vaccinations. Two randomized controlled trials demonstrated the efficacy of acetaminophen prophylaxis in preventing fever after whole cell pertussis vaccination, but acetaminophen prophylaxis has not been evaluated for prevention of fever following contemporary vaccines recommended for infants in the United States. METHODS Children six weeks through nine months of age were randomized 1:1 to receive up to five doses of acetaminophen (10-15 mg per kg… CONTINUE READING
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