A Randomized-Controlled Trial of Prophylactic Hydrocortisone Supplementation for the Prevention of Hypotension in Extremely Low Birth Weight Infants

@article{Efird2005ART,
  title={A Randomized-Controlled Trial of Prophylactic Hydrocortisone Supplementation for the Prevention of Hypotension in Extremely Low Birth Weight Infants},
  author={Meica M Efird and Ann T Heerens and Phillip V. Gordon and Carl L. Bose and David Alexander Young},
  journal={Journal of Perinatology},
  year={2005},
  volume={25},
  pages={119-124}
}
OBJECTIVE:Extremely low birth weight (ELBW) infants are at risk for hypotension. Abnormal adrenal function may play a role in the pathogenesis of hypotension, and therefore, the administration of hydrocortisone (HC) may be an effective treatment for hypotension in some infants. However, the efficacy of prophylactic HC to prevent the use of vasopressors for a defined hypotensive state has not been studied. We conducted a randomized-controlled trial to determine the potential role on adrenal… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 39 CITATIONS

Cortisol precursors in neonates with vasopressor-resistant hypotension in relationship to demographic characteristics.

  • Abdelmoneim Khashana, Hoda A.M. Ahmed, +4 authors Mitchell Hallman
  • Medicine
  • The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2018

Cardiovascular Drug Therapy for Human Newborn: Review of Pharmacodynamic Data.

VIEW 1 EXCERPT
CITES BACKGROUND

Adrenocortical insufficiency and refractory hypotension in preterm infants.

  • Pak Cheung Ng
  • Medicine
  • Archives of disease in childhood. Fetal and neonatal edition
  • 2016

References

Publications referenced by this paper.
SHOWING 1-10 OF 42 REFERENCES

Blood pressure in the very low birth weight neonate.

VIEW 1 EXCERPT

Refractory hypotension in preterm infants with adrenocortical insufficiency.