A Randomized Controlled Pilot Trial of Azithromycin or Artesunate Added to Sulfadoxine-Pyrimethamine as Treatment for Malaria in Pregnant Women

@article{Kalilani2007ARC,
  title={A Randomized Controlled Pilot Trial of Azithromycin or Artesunate Added to Sulfadoxine-Pyrimethamine as Treatment for Malaria in Pregnant Women},
  author={Linda V Kalilani and Innocent A Mofolo and Marjorie Chaponda and Stephen J Rogerson and Alisa P. Alker and Jesse J. Kwiek and Steven Richard Meshnick},
  journal={PLoS ONE},
  year={2007},
  volume={2},
  pages={846 - 853}
}
OBJECTIVE New anti-malarial regimens are urgently needed in sub-Saharan Africa because of the increase in drug resistance. We investigated the safety and efficacy of azithromycin or artesunate combined with sulfadoxine-pyrimethamine used for treatment of malaria in pregnant women in Blantyre, Malawi. METHODS/FINDINGS This was a randomized open-label clinical trial, conducted at two rural health centers in Blantyre district, Malawi. A total of 141 pregnant women with uncomplicated Plasmodium… CONTINUE READING

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