A Randomized, Prospective, Double‐Blind Study on the Efficacy of Dead Sea Salt Nasal Irrigations

@article{Friedman2006ARP,
  title={A Randomized, Prospective, Double‐Blind Study on the Efficacy of Dead Sea Salt Nasal Irrigations},
  author={Michael Friedman and Ramakrishnan Vidyasagar and Ninos J Joseph},
  journal={The Laryngoscope},
  year={2006},
  volume={116}
}
Objective: The objective of this randomized, prospective, double‐blind study was to compare nasal irrigation using hypertonic Dead Sea salt (DSS) solution with hypertonic saline in the treatment of chronic rhinosinusitis and improvement of quality of life (QOL). 

Dead Sea salt irrigations vs saline irrigations with nasal steroids for symptomatic treatment of chronic rhinosinusitis: a randomized, prospective double‐blind study

This study aimed to compare the efficacy of Dead Sea salt (DSS) irrigations and DSS nasal spray vs saline irrigation and topical nasal steroid spray in the treatment of symptoms of CRS.

Effect of Budesonide Added to Large-Volume, Low-pressure Saline Sinus Irrigation for Chronic Rhinosinusitis: A Randomized Clinical Trial

This study shows that budesonide in saline nasal lavage results in clinically meaningful benefits beyond the benefits of saline alone for patients with CRS, and given the imprecision in the treatment effect, further research is warranted.

The Potential Role of Hyaluronan in Minimizing Symptoms and Preventing Exacerbations of Chronic Rhinosinusitis

The results of this study suggested that intermittent treatment with topical 9-mg sodium hyaluronate plays a role in minimizing symptoms and could prevent exacerbations of CRS.

Comparison on the efficacy of dexpanthenol in sea water and saline in postoperative endoscopic sinus surgery.

The efficacy of dexpanthenol was comparable to nasal saline irrigation in the postoperative care of sinusitis patients following endoscopic sinus surgery and may be useful in young children and complicated cases.

Optimal Device and Regimen of Nasal Saline Treatment for Sinonasal Diseases: Systematic Review

Nasal saline treatment is recommended for treating most sinonasal diseases and Buffered isotonic saline was more tolerable than nonbuffered or hypertonic saline.

Nasal irrigation: From empiricism to evidence-based medicine. A review.

A two‐center, assessor‐blinded, prospective trial evaluating the efficacy of a novel hypertonic draining cream for cellulite reduction: A Clinical and instrumental (Antera 3D CS) assessment

A new hypertonic topical product with draining action (HTC) containing NaCl 13%, escine, caffeine, and beta‐sitosterol has been recently developed and a 28‐day double‐blind placebo‐controlled study has shown that this cream is able to reduce thigh circumference and the thickness of adipose tissue.

Commentary on ‘Nasal saline irrigations for the symptoms of chronic rhinosinusitis’

This is a commentary on a Cochrane review, published in this issue of EBCH, first published as: Nasal saline irrigations for the symptoms of chronic rhinosinusitis.
...

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