A Randomized, Double-Blinded, Clinical Trial on Effects of a Vitis vinifera Extract on Cognitive Function in Healthy Older Adults

@inproceedings{Calapai2017ARD,
  title={A Randomized, Double-Blinded, Clinical Trial on Effects of a Vitis vinifera Extract on Cognitive Function in Healthy Older Adults},
  author={Gioacchino Calapai and Francesco Paolo Bonina and Andrea Bonina and Luisa Rizza and Carmen Mannucci and Vincenzo Arcoraci and Germana Lagan{\`a} and Angela Alibrandi and Concetta Pollicino and Santi Inferrera and Umberto Alecci},
  booktitle={Front. Pharmacol.},
  year={2017}
}
Introduction: Gradual population aging is creating a new set of needs in the general population. Memory capacity decreases with age, and memory deficits are considered an early symptom of Alzheimer's Disease (AD), one of the most prevalent cognitive disorders in older people. Numerous studies have shown that grape polyphenolic compounds (GPs) are able to attenuate cognitive impairment and reduce brain lesions in experimental AD animal models. These GP effects are associated with improvement in… CONTINUE READING