A Randomized, Double-Blind Pilot Study of Dexmedetomidine Versus Midazolam for Intensive Care Unit Sedation

@article{MacLaren2015ARD,
  title={A Randomized, Double-Blind Pilot Study of Dexmedetomidine Versus Midazolam for Intensive Care Unit Sedation},
  author={Robert MacLaren and Candice R Preslaski and Scott W. Mueller and Tyree H. Kiser and Douglas N. Fish and James C Lavelle and Stephen P Malkoski},
  journal={Journal of Intensive Care Medicine},
  year={2015},
  volume={30},
  pages={167 - 175}
}
Introduction: Sedation with dexmedetomidine may facilitate ventilator liberation and limit the occurrence of delirium. No trial has assessed patient recall or the development of psychological outcomes after dexmedetomidine sedation. This pilot study evaluated whether transitioning benzodiazepine sedation to dexmedetomidine alters patient recall and the incidence of anxiety, depression, or acute stress disorder (ASD). Methods: This investigation was a randomized, double-blind, single-center… 

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