A Randomised Controlled Trial of Triple Antiplatelet Therapy (Aspirin, Clopidogrel and Dipyridamole) in the Secondary Prevention of Stroke: Safety, Tolerability and Feasibility

@article{Sprigg2008ARC,
  title={A Randomised Controlled Trial of Triple Antiplatelet Therapy (Aspirin, Clopidogrel and Dipyridamole) in the Secondary Prevention of Stroke: Safety, Tolerability and Feasibility},
  author={Nikola Sprigg and L J Gray and Tim England and Mark R. Willmot and Lian Zhao and Gillian M. Sare and Philip Michael William Bath},
  journal={PLoS ONE},
  year={2008},
  volume={3},
  pages={34 - 40}
}
BACKGROUND Aspirin, dipyridamole and clopidogrel are effective in secondary vascular prevention. Combination therapy with three antiplatelet agents might maximise the benefit of antiplatelet treatment in the secondary prevention of ischaemic stroke. METHODOLOGY/PRINCIPAL FINDINGS A randomised, parallel group, observer-blinded phase II trial compared the combination of aspirin, clopidogrel and dipyridamole with aspirin alone. Adult patients with ischaemic stroke or transient ischaemic attack… CONTINUE READING

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