A Randomised, Controlled Study of Dietary Intervention in Autistic Syndromes

@article{Knivsberg2002ARC,
  title={A Randomised, Controlled Study of Dietary Intervention in Autistic Syndromes},
  author={A M Knivsberg and Karl Ludvig Reichelt and T. H{\O}ien and M. N{\O}dland},
  journal={Nutritional Neuroscience},
  year={2002},
  volume={5},
  pages={251 - 261}
}
Abstract Impaired social interaction, communication and imaginative skills characterize autistic syndromes. In these syndromes urinary peptide abnormalities, derived from gluten, gliadin, and casein, are reported. They reflect processes with opioid effect. The aim of this single blind study was to evaluate effect of gluten and casein-free diet for children with autistic syndromes and urinary peptide abnormalities. A randomly selected diet and control group with 10 children in each group… 
Effect of a Dietary Intervention on Autistic Behavior
Autistic syndromes are characterized by impaired social, communicative, and imaginative skills. Urinary peptide abnormalities, in part due to gluten and casein, have been detected in some individuals
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TLDR
The impact of dietary intervention made using dietary guide books found to be useful to reduce various behavior symptoms among the selected autistic children.
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TLDR
The data remains insufficient to support the use of GCFD to improve the symptoms of ASD in children, and the role of the gluten- and casein-free diet on the management of ASD remains unchanged.
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TLDR
The results do not support use of a GFCF diet in ASD, and it is possible that a greater period of time is required for treatment before gains can be observed.
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TLDR
Analysis of the effects of gluten-free and casein-free diets on children with autism found that the majority of identified studies evaluating GFCF diet outcomes failed to meet basic methodological standards of interventional science, and Rigorous scientific evaluations partly failed to confirm therapeutic effects of the G FCF diet.
The Role of Gluten in Autism.
TLDR
A gluten-free diet has yielded positive outcomes giving hope in developing therapy for ASD, shows improvement in behavioral changes and reduction in malnutrition seemingly associated with the allergies or food intolerance to gluten.
From Diet to Detox: Controversial Therapies in Autistic Spectrum Disorders
TLDR
The current fad for unorthodox biomedical interventions in autism includes an eclectic collection of therapies which have no coherent scientific rationale and for which evidence of either efficacy or safety is lacking.
Gluten- and casein-free diet and autism spectrum disorders in children: a systematic review
TLDR
Overall, there is little evidence that a GFCF diet is beneficial for the symptoms of ASD in children.
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