A RP-HPLC method development and validation for simultaneous estimation of metformin HCl and rosiglitazone in bulk and tablet dosage form


A rapid reverse phase high performance liquid chromatography method has been developed and validated for the determination of Metformin HCl and Rosiglitazone maleate in combined tablet dosage form. Isocratic chromatography was performed on a Symmetry C18 column (150X4.6mm, 5μm, XTerra) with a mobile phase consist of 70:30v/v Methanol : Phosphate buffer (pH… (More)


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