A Quest for Better Mouse Models of Breast and Ovarian Cancers

Abstract

Inheritedmutations in the BRCA1 (breast cancer 1, early onset) gene increase the risk of female breast and ovarian cancers. About 65% and 40% of females who inherit BRCA1 mutations will develop breast and ovarian cancer, respectively (Antoniou et al., 2003). To address specific roles of BRCA1 in the normal development and cancer pathogenesis, a number of… (More)
DOI: 10.1016/j.ebiom.2015.09.017

Topics

Cite this paper

@inproceedings{Harlan2015AQF, title={A Quest for Better Mouse Models of Breast and Ovarian Cancers}, author={Blaine A. Harlan and Alexander Yu Nikitin}, booktitle={EBioMedicine}, year={2015} }