A Pulse of the Drosophila Hox Protein Abdominal-A Schedules the End of Neural Proliferation via Neuroblast Apoptosis

@article{Bello2003APO,
  title={A Pulse of the Drosophila Hox Protein Abdominal-A Schedules the End of Neural Proliferation via Neuroblast Apoptosis},
  author={Bruno C. Bello and Frank Hirth and Alex P Gould},
  journal={Neuron},
  year={2003},
  volume={37},
  pages={209-219}
}
Postembryonic neuroblasts are stem cell-like precursors that generate most neurons of the adult Drosophila central nervous system (CNS). Their capacity to divide is modulated along the anterior-posterior body axis, but the mechanism underlying this is unclear. We use clonal analysis of identified precursors in the abdomen to show that neuron production stops because the cell death program is activated in the neuroblast while it is still engaged in the cell cycle. A burst of expression of the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 81 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Transcription of the Drosoph - cell movement in the formation of the imaginal nervous system in ila CKI gene dacapo is regulated by a modular array of cis - regulatory Drosophila melanogaster

  • D. R. Kankel, T. H. Liu, L. Li, H. Vaessin
  • Dev . Biol .
  • 2002

Drosoph - scriptional control during Drosophila development

  • T. tran-Isshiki, B. Pearson, S. Holbrook, C. Q. Doe
  • Curr . Opin . Cell ila neuroblasts sequentially…
  • 2001

Similar Papers

Loading similar papers…