A Proximity-Based Method to Identify Genomic Regions Correlated with a Continuously Varying Environmental Variable

  title={A Proximity-Based Method to Identify Genomic Regions Correlated with a Continuously Varying Environmental Variable},
  author={Cornelia Di Gaetano and Giuseppe Matullo and Alberto Piazza and Moreno Ursino and Mauro Gasparini},
  journal={Evolutionary Bioinformatics Online},
  pages={29 - 42}
Knowledge of markers in the human genome which show spatial patterns and display extreme correlation with different environmental determinants play an important role in understanding the factors which affect the biological evolution of our species. We used the genotype data of more than half a million single nucleotide polymorphisms (SNPs) from the data set Human Genome Diversity Panel (HGDP-CEPH-CEPH) and we calculated Spearman's correlation between absolute latitude and one of the two allele… 

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