A Protocol for Computer-Based Protein Structure and Function Prediction

@inproceedings{Roy2011APF,
  title={A Protocol for Computer-Based Protein Structure and Function Prediction},
  author={Ambrish Roy and Dong Xu and Jonathan Poisson and Yang Arthur Zhang},
  booktitle={Journal of visualized experiments : JoVE},
  year={2011}
}
Genome sequencing projects have ciphered millions of protein sequence, which require knowledge of their structure and function to improve the understanding of their biological role. Although experimental methods can provide detailed information for a small fraction of these proteins, computational modeling is needed for the majority of protein molecules which are experimentally uncharacterized. The I-TASSER server is an on-line workbench for high-resolution modeling of protein structure and… CONTINUE READING
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COFACTOR: protein-ligand binding site predictions by global structure similarity match and local geometry refinement

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