A Prospective Study to Monitor for Tuberculosis During Anti-tumour Necrosis Factor Therapy in Patients With Inflammatory Bowel Disease and Immune-mediated Inflammatory Diseases

@article{Lee2018APS,
  title={A Prospective Study to Monitor for Tuberculosis During Anti-tumour Necrosis Factor Therapy in Patients With Inflammatory Bowel Disease and Immune-mediated Inflammatory Diseases},
  author={Choon Kin Lee and Sunny Hei Wong and Grace Lui and Whitney Tang and Lai S Tam and Margaret Ip and Esther Hiu Yee Hung and Minhu Chen and Justin Che-yuen Wu and Siew Chien Ng},
  journal={Journal of Crohn's and Colitis},
  year={2018},
  volume={12},
  pages={954–962}
}
Background Biologic therapies have revolutionised the treatment of immune-mediated diseases including inflammatory bowel disease [IBD] and rheumatological disorders. However, biologic treatments are associated with an increased risk of reactivation of latent tuberculosis. Data from regular monitoring for latent tuberculosis infection [LTBI] during biologic treatment are lacking. Methods Consecutive patients eligible for biologic therapies were screened for LTBI and prospectively followed up… Expand
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