A Prospective Evaluation of a multisite Cryptococcal Screening and Treatment program in HIV clinics in Uganda.

Abstract

BACKGROUND Cryptococcus is a leading cause of AIDS-related mortality. Cryptococcal antigen (CrAg) is detectable in blood before meningitis onset, and predicts death. CrAg screening amongst those with advanced HIV, and treatment of those CrAg+ with fluconazole has demonstrated survival benefit. However, implementation and widespread uptake have been slow… (More)
DOI: 10.1097/QAI.0000000000001669

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