A Proposed Classification of the Immunological Diseases

  title={A Proposed Classification of the Immunological Diseases},
  author={Dennis McGonagle and Michael F McDermott},
  journal={PLoS Medicine},
  pages={67 - 69}
August 2006 | Volume 3 | Issue 8 | e297 A century ago Paul Ehrlich proposed that immune reactivity against self, which he called “horror autotoxicus” and which is now called autoimmunity, would be incompatible with life because of potentially devastating consequences for the host. But Ehrlich was proven wrong after the demonstration of autoantibodies and the emergence of a theoretical basis for autoreactivity [1]. Conceptually, autoimmunity is viewed as a defect of either B or T lymphocyte… CONTINUE READING
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