A Primer on Vesicle Budding

@article{Springer1999APO,
  title={A Primer on Vesicle Budding},
  author={Sebastian Springer and Anne Spang and Randy Schekman},
  journal={Cell},
  year={1999},
  volume={97},
  pages={145-148}
}
  • Sebastian Springer, Anne Spang, Randy Schekman
  • Published in Cell 1999
  • Biology, Medicine
  • A basic scheme of transport vesicle formation is beginning to emerge (Figure 1Figure 1). Its central feature is the priming complex: an association of a small GTPase, a primer protein, and one or several other subunits of the vesicular coat, including a GTPase-activating protein. Formation of this complex is coat- and membrane-specific due to the restricted overlapping cellular distributions of primer proteins and GTPases in their GTP state; functionally essential vesicle proteins may prove… CONTINUE READING

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