A Preliminary Study of Subsymptom Threshold Exercise Training for Refractory Post-Concussion Syndrome

  title={A Preliminary Study of Subsymptom Threshold Exercise Training for Refractory Post-Concussion Syndrome},
  author={John J Leddy and Karl F. Kozlowski and James P. Donnelly and David Robert Pendergast and Leonard H. Epstein and Barry S Willer},
  journal={Clinical Journal of Sport Medicine},
Objective:To evaluate the safety and effectiveness of subsymptom threshold exercise training for the treatment of post-concussion syndrome (PCS). Design:Prospective case series. Setting:University Sports Medicine Concussion Clinic. Participants:Twelve refractory patients with PCS (6 athletes and 6 nonathletes). Intervention:Treadmill test to symptom exacerbation threshold (ST) before and after 2 to 3 weeks of baseline. Subjects then exercised 5 to 6 days per week at 80% ST heart rate (HR) until… 

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