A Preliminary Comparative Assessment of the Role of CD8+ T Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis

@article{Brenu2016APC,
  title={A Preliminary Comparative Assessment of the Role of CD8+ T Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis},
  author={E. Brenu and S. Broadley and T. Nguyen and S. Johnston and S. Ramos and D. Staines and S. Marshall-Gradisnik},
  journal={Journal of Immunology Research},
  year={2016},
  volume={2016}
}
  • E. Brenu, S. Broadley, +4 authors S. Marshall-Gradisnik
  • Published 2016
  • Medicine
  • Journal of Immunology Research
  • Background. CD8+ T cells have putative roles in the regulation of adaptive immune responses during infection. The purpose of this paper is to compare the status of CD8+ T cells in Multiple Sclerosis (MS) and Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). Methods. This preliminary investigation comprised 23 CFS/ME patients, 11 untreated MS patients, and 30 nonfatigued controls. Whole blood samples were collected from participants, stained with monoclonal antibodies, and analysed on… CONTINUE READING
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    References

    SHOWING 1-10 OF 59 REFERENCES
    Immune regulation of multiple sclerosis by CD8+ T cells
    • 42
    Immunological abnormalities as potential biomarkers in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
    • 189
    • PDF
    Relapses in multiple sclerosis are associated with increased CD8+ T-cell mediated cytotoxicity in CSF
    • 59
    • Highly Influential
    The IL-7Rα Pathway Is Quantitatively and Functionally Altered in CD8 T Cells in Multiple Sclerosis
    • 27
    • Highly Influential
    • PDF