A Preliminary Assessment of Atracurium, a New Competitive Neuromuscular Blocking Agent

@article{Coker1981APA,
  title={A Preliminary Assessment of Atracurium, a New Competitive Neuromuscular Blocking Agent},
  author={G. Coker and G. Dewar and R. Hughes and T. M. Hunt and J. Payne and J. Stenlake and R. D. Waigh},
  journal={Acta Anaesthesiologica Scandinavica},
  year={1981},
  volume={25}
}
  • G. Coker, G. Dewar, +4 authors R. D. Waigh
  • Published 1981
  • Medicine
  • Acta Anaesthesiologica Scandinavica
  • Atracurium besylate, 2,2′‐(3,1 l‐dioxo‐4,10‐dioxatridecylene}‐bis‐[6,7‐dimethoxy‐l‐(3,4‐dimethoxybenzyl)‐2‐methyl 1,2,3,4‐tetrahydroisoquinolinium] dibenzenesulphonate is a potent non‐depolarising (competitive) neuromuscular blocking agent in the cat, monkey, dog and anaesthetised man. In man, it caused complete paralysis of the tetanic response of the adductor pollicis muscles at doses of 0.2 mg/kg. Blockade was of medium duration with rapid spontaneous recovery, and was readily reversed by… CONTINUE READING
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