A Prediction Model for Bacterial Etiology in Acute Exacerbations of COPD

  title={A Prediction Model for Bacterial Etiology in Acute Exacerbations of COPD},
  author={Hartmut M Lode and Markus Allewelt and Sarah Balk and Andres de Roux and Harald Mauch and Michael S. Niederman and Malina Schmidt-Ioanas},
Bacteria play a leading role in acute exacerbations of chronic obstructive pulmonary disease (COPD), but we lack predictors of bacterial etiology. We developed a prediction model for infection with gram-negative enteric bacteria (GNEB) and Pseudomonas aeruginosa. Clinical presentation, sputum characteristics, microbial sputum patterns, lung function and previous and concomitant medication were prospectively recorded in patients with moderate to severe exacerbation of COPD. Risk factors for a… CONTINUE READING


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