A Preclinical Study of the Safety and Efficacy of Occlusin™ 500 Artificial Embolization Device in Sheep

@article{Owen2011APS,
  title={A Preclinical Study of the Safety and Efficacy of Occlusin™ 500 Artificial Embolization Device in Sheep},
  author={Richard J. T. Owen and Patrick N. Nation and Robert Polakowski and Jennifer A. Biliske and Paul B. Tiege and Irwin J. Griffith},
  journal={CardioVascular and Interventional Radiology},
  year={2011},
  volume={35},
  pages={636-644}
}
This study evaluated the safety, effectiveness, and biodegradation of a new embolic agent, Occlusin™ 503 Artificial Embolization Device (OCL 503). The agent consists of biodegradable poly-lactic-co-glycolic acid microspheres (150–212 μm) coated with type I bovine collagen and was compared with Embosphere® Microspheres (300–500 μm) in this controlled study of uterine artery embolization (UAE) in sheep. Unilateral UAE was performed in 32 adult ewes randomly assigned. Vessels were embolized to… CONTINUE READING
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