A Practical Guide for Treatment of Pain in Patients with Systemic Mast Cell Activation Disease.
@article{Wirz2017APG, title={A Practical Guide for Treatment of Pain in Patients with Systemic Mast Cell Activation Disease.}, author={S. Wirz and G. Molderings}, journal={Pain physician}, year={2017}, volume={20 6}, pages={ E849-E861 } }
Systemic mast cell activation disease (MCAD, a subclass of mastocytosis), which has a prevalence of around 17% (at least in the German population), is characterized by accumulation of genetically altered dysfunctional mast cells with abnormal release of these cells' mediators. Since mast cells affect functions in potentially every organ system, often without causing abnormalities in routine laboratory or radiologic testing, this disease has to be considered routinely in the differential… CONTINUE READING
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